March 24, 2024
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How to Detox Spike Protein from Body – Dr Mercola

One Day MD | by Dr. Frank Yap, MD | April 28, 2023

The spike protein is naturally found in SARS-CoV-2, no matter the variant. In its native form in SARS-CoV-2, the spike protein is responsible for the pathologies of the viral infection.

In its wild form it’s known to open the blood-brain barrier, cause cell damage (cytotoxicity) and, as Dr. Robert Malone, the inventor of the mRNA and DNA vaccine core platform technology (R), said in a commentary on News Voice, “is active in manipulating the biology of the cells that coat the inside of your blood vessels — vascular endothelial cells, in part through its interaction with ACE2, which controls contraction in the blood vessels, blood pressure and other things.” (R)

It’s also been revealed that the spike protein on its own is enough to cause inflammation and damage to the vascular system, even independent of a virus. (R)

As of March 13, 2023, federal data published by the US CDC found that 14.8% (National Estimate) of adults who previously had a COVID-19 infection are currently experiencing symptoms of long COVID. 

The World Council for Health (WCH), a worldwide coalition of health-focused organizations and civil society groups that seek to broaden public health knowledge, has released a spike protein detox guide, which provides straightforward steps you can take to potentially lessen the effects of toxic spike protein. You can view their full guide of natural remedies, including dosages, at the end of this article.

Why Should You Consider a Spike Protein Detox?

Spike proteins can circulate in your body after infection or injection, causing damage to cells, tissues and organs. “Spike protein is a deadly protein,” Dr. Peter McCullough, an internist, cardiologist and trained epidemiologist, says in a video. (6) It may cause inflammation and clotting in any tissue in which it accumulates.(7) 

For instance, Pfizer’s biodistribution study, which was used to determine where the injected substances end up in the body, showed the COVID spike protein from the shots accumulated in “quite high concentrations” in the ovaries.(8)

Further, a Japanese biodistribution study for Pfizer’s jab found that vaccine particles move from the injection site to the blood, after which circulating spike proteins are free to travel throughout the body, including to the ovaries, liver, neurological tissues and other organs.(9) WCH noted:(10) 

“The virus spike protein has been linked to adverse effects, such as: blood clots, brain fog, organizing pneumonia, and myocarditis. It is probably responsible for many of the Covid-19 [injection] side effects … Even if you have not had any symptoms, tested positive for Covid-19, or experienced adverse side effects after a jab, there may still be lingering spike proteins inside your body.

In order to clear these after the jab or an infection, doctors and holistic practitioners are suggesting a few simple actions. It is thought that cleansing the body of spike protein … as soon as possible after an infection or jab may protect against damage from remaining or circulating spike proteins.”

Spike Protein Inhibitors and Neutralizers

A group of international doctors and holistic practitioners who have experience helping people recover from COVID-19 and post-injection illness compiled natural options for helping to reduce your body’s spike protein load. The following are spike protein inhibitors, which means they inhibit the binding of the spike protein to human cells:

  • Prunella vulgaris
  • Pine needles
  • Emodin
  • Neem
  • Dandelion leaf extract
  • Ivermectin

Ivermectin, for example, docks to the SARS-CoV-2 spike receptor-bending domain attached to ACE2, which may interfere with its ability to attach to the human cell membrane.11 They also compiled a list of spike protein neutralizers, which render it unable to cause further damage to cells. This includes:

  • N-acetylcysteine (NAC)
  • Glutathione
  • Fennel tea
  • Star anise tea
  • Pine needle tea
  • St. John’s wort
  • Comfrey leaf
  • Vitamin C

The plant compounds in the table above contain shikimic acid, which may counteract blood clot formation and reduce some of the spike protein’s toxic effects. Nattokinase, a form of fermented soy, may also help to reduce the occurrence of blood clots.12

How to Protect Your ACE2 Receptors and Detox IL-6

Spike protein attaches to your cells’ ACE2 receptors, impairing the receptors’ normal functioning. This blockage may alter tissue functioning and could be responsible for triggering autoimmune disease or causing abnormal bleeding or clotting, including vaccine-induced thrombotic thrombocytopenia.

Ivermectin, hydroxychloroquine (with zinc), quercetin (with zinc) and fisetin (a flavonoid) are examples of substances that may naturally protect your ACE2 receptors.13 Ivermectin works in this regard by binding to ACE2 receptors, preventing the spike protein from doing so.14

Interleukin 6 (IL-6) is a proinflammatory cytokine that is expressed post-injection and levels increase in those with COVID-19. It’s for this reason that the World Health Organization recommends IL-6 inhibitors for people who are severely ill with COVID-19.15 Many natural IL-6 inhibitors, or anti-inflammatories, exist and may be useful for those seeking to detox from COVID-19 or COVID-19 injections:16

  • Boswellia serrata (frankincense)
  • Dandelion leaf extract
  • Black cumin (Nigella sativa)
  • Curcumin
  • Krill oil and other fatty acids
  • Cinnamon
  • Fisetin
  • Apigenin
  • Quercetin
  • Resveratrol
  • Luteolin
  • Vitamin D3 (with vitamin K)
  • Zinc
  • Magnesium
  • Jasmine tea
  • Spices
  • Bay leaves
  • Black pepper
  • Nutmeg
  • Sage

How to Detox From Furin and Serine Protease

To gain entry into your cells, SARS-CoV-2 must first bind to an ACE2 or CD147 receptor on the cell. Next, the spike protein subunit must be proteolytically cleaved (cut). Without this protein cleavage, the virus would simply attach to the receptor and not get any further.

“The furin site is why the virus is so transmissible, and why it invades the heart, the brain and the blood vessels,” Dr. Steven Quay, a physician and scientist, explained at a GOP House Oversight and Reform Subcommittee on Select Coronavirus Crisis hearing.17

The existence of a novel furin cleavage site on SARS-CoV-2, while other coronaviruses do not contain a single example of a furin cleavage site, is a significant reason why many believe SARS-CoV-2 was created through gain-of-function (GOF) research in a laboratory. Natural furin inhibitors, which prevent cleavage of the spike protein, can help you detox from furin and include:18

  • Rutin
  • Limonene
  • Baicalein
  • Hesperidin

Serine protease is another enzyme that’s “responsible for the proteolytic cleavage of the SARS-CoV-2 spike protein, enabling host cell fusion of the virus.”19 Inhibiting serine protease may therefore prevent spike protein activation and viral entry into cells. WCH compiled several natural serine protease inhibitors, which include:20

  • Green tea
  • Potato tubers
  • Blue green algae
  • Soybeans
  • N-acetyl cysteine (NAC)
  • Boswellia

Time-Restricted Eating and Healthy Diet for All

In addition to the targeted substances mentioned above, WCH was wise to note that a healthy diet is the first step to a healthy immune system. Reducing your consumption of processed foods and other proinflammatory foods, including vegetable (seed) oils, is essential for an optimal immune response.

Time-restricted eating, which means condensing your meals into a six- to eight-hour window, is also beneficial. This will improve your health in a variety of ways, primarily by improving your mitochondrial health and metabolic flexibility. It can also increase autophagy,21 which helps your body clear out damaged cells. As noted by WCH:22 

“This method … is used to induce autophagy, which is essentially a recycling process that takes place in human cells, where cells degrade and recycle components. Autophagy is used by the body to eliminate damaged cell proteins and can destroy harmful viruses and bacteria post-infection.”

Another strategy to boost your health and longevity, and possibly to help detox spike protein,23 is regular sauna usage. As your body is subjected to reasonable amounts of heat stress, it gradually becomes acclimated to the heat, prompting a number of beneficial changes to occur in your body.

These adaptations include increased plasma volume and blood flow to your heart and muscles (which increase athletic endurance) along with increased muscle mass due to greater levels of heat-shock proteins and growth hormone.24 It’s a powerful detoxification method due to the sweating it promotes. 

Top 10 Spike Protein Detox Essentials — and the Full Guide

Below you can find WCH’s full guide of useful substances to detox from toxic spike proteins, including recommended doses, which you can confirm with your holistic health care practitioner. If you’re not sure where to start, the following 10 compounds are the “essentials” when it comes to spike protein detox. This is a good place to begin as you work out a more comprehensive health strategy:

  1. Vitamin D
  2. NAC
  3. Ivermectin
  4. Nigella seed
  5. Quercetin
  6. Zinc
  7. Vitamin C
  8. Magnesium
  9. Curcumin
  10. Milk thistle extract

World Council for Health’s Spike Protein Detox Summary Guide

Substance: Ivermectin

Natural Source(s):

Where to Get: On prescription

Recommended Dose: 0.4mg/kg weekly for 4 weeks. If symptomatic, refer to the FLCCC I-Recover Protocol.

*Check package instructions to determine if there are contraindications prior to use.

Substance: Hydroxychloroquine

Natural Source(s):

Where to Get: On prescription

Recommended Dose: 200mg weekly for 4 weeks.

*Check package instructions to determine if there are contraindications prior to use

Substance: Vitamin C

Natural Source(s): Citrus fruits (e.g. oranges) and vegetables (broccoli, cauliflower, brussel sprouts)

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: 6-12g daily (divided evenly between sodium ascorbate (several grams), liposomal vitamin C (3-6g) & ascorbyl palmitate (1 – 3g)

Substance: N-Acetyl Cysteine (NAC)

Natural Source(s): High-protein foods (beans, lentils, spinach, bananas, salmon, tuna)

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: Up to 1200mg daily (in divided doses)

Substance: Nattokinase

Natural Source(s): Natto (Japanese soybean dish)

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: As directed on supplement

Substance: Quercetin (Flavonoid)

Natural Source(s): Citrus fruits, onions, parsley, red wine

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: Up to 500mg twice daily, Consume with Zinc, Bromelain and Vitamin C

Substance: Fisetin (Flavonoid)

Natural Source(s): Fruits: strawberries, apples, mangoes Vegetables: onions, nuts, wine

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: Up to 100mg daily (Consume with fats)

Substance: Resveratrol

Natural Source(s): Peanuts, grapes, red wine, blueberries, cocoa

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: Up to 1500 mg daily for up to 3 months

Substance: Vitamin D3

Natural Source(s): Fatty fish, fish liver oils, milk, eggs

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: 5000 IU daily  (Consume with K2)

Substance: Vitamin K2

Natural Source(s): green leafy vegetables

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: 90-120mcg daily  (90 for women, 120 for men)

Substance: Zinc

Natural Source(s): Red meat, poultry, oysters, whole grains, milk products

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: 11-40mg daily

Substance: Magnesium

Natural Source(s): Greens, whole grains, nuts

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: Up to 350mg daily

Substance: Blue Green Algae

Natural Source(s): Cyanobacteria

Where to Get: Supplement: health food stores, pharmacies, dietary supplement stores, online

Recommended Dose: 1-10 grams daily

Substance: Green Tea

Natural Source(s): Camellia sinensis plant leaves

Where to Get: Grocery stores, health food stores

Recommended Dose: Up to 8 cups of tea a day or as directed on supplement

Substance: Fish Oil

Natural Source(s): Fatty / Oily fish

Where to Get: Grocery stores, health food stores

Recommended Dose: Up to 2000mg daily

Substance: Black Cumin (Nigella Sativa)

Natural Source(s): Buttercup plant family

Where to Get: Grocery stores, health food stores

Recommended Dose: 

Substance: Curcumin

Natural Source(s): Turmeric

Where to Get: Grocery stores, health food stores

Recommended Dose: 

Substance: Soybeans (organic)

Natural Source(s): Soybeans (organic)

Where to Get: Grocery stores, health food stores

Recommended Dose: 


Treating Long-Haul COVID

One of the primary complaints of those struggling with what we’re now calling “long-haul COVID” is fatigue, a lack of energy to do even the most basic things. Since mitochondria are responsible for 90% of the energy production in your body, it stands to reason that impaired energy production in the mitochondria, or more simply, mitochondrial dysfunction, is at play.

The challenge is how to recover that function. One fascinating drug that can help in this regard is methylene blue, which helps mitochondrial respiration and improves brain energy metabolism. Methylene blue is actually the parent molecule for hydroxychloroquine and chloroquine, off-patent drugs commonly used to treat not only malaria but also COVID-19.

Best known as a fish tank antiseptic and textile dye for blue jeans, it was actually the first synthetic drug in modern history, developed in 1876. Since then, we’ve discovered it has many really important medicinal benefits. Importantly, it’s the only known antidote for metabolic poisons, i.e., any poison that interferes with oxygen transport or displaces oxygen, either from the blood or from the mitochondria.

Basically, as an electron cycler, methylene blue acts like a battery, but unlike other compounds that do the same thing, it doesn’t cause damaging oxidation in the process. You can review my interview with Dr. Francisco Gonzalez Lima here for more information.

If anything interferes with oxygenation or cellular respiration, such as cyanide, methylene blue is able to bypass that point of interference through electron cycling, thus allowing mitochondrial respiration, oxygen consumption and energy production to function as it normally would. And, the effect is typically felt within hours, as it increases, by about 30%, the ability of the mitochondria to produce ATP in the electron transport chain. 

Sources and References:

Source: How to Detox Spike Protein from Body – Dr Mercola (onedaymd.com)

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